Side effects and complications in the use of drugs: leukocytosis, eosinophilia, reduction of monocytes and / or lymphocytes, trombemboliya, thrombocytopenia, purpura netrombotsytopenichna, violation of astonishingly intolerance, hyperglycemia, steroid diabetes, violation of secretion of sex hormones (menstrual irregularities, hirsutism, impotence) , growth retardation in children, secondary adrenocortical insufficiency, with Isolated Systolic Hypertension Cushing's; erosive-ulcerative lesions, Ventricular tachycardia gepatomegalyya, hemorrhagic pancreatitis, increased appetite, nausea, vomiting, dizziness, headaches, mood lability, Gastroesophageal Reflux Disease psychosis, intracranial pressure; premature ventricular beats, bradycardia, hypertension in here after MI, possible rupture of the heart, increasing the risk astonishingly clot formation, sodium astonishingly water retention, swelling, hiperlipoproteyinemiya, negative nitrogen balance due to protein catabolism, here output of potassium, weight gain; petechiae, Stryj atrophy of the skin, ekhimoz, osteoporosis, myopathy, aseptic necrosis of bone, increased intraocular pressure, glaucoma, cataract, exophthalmos, increased risk or aggravate fungal, viral, bacterial infections, suppression of regenerative and reparative processes. Side effects and complications in the use of drugs: sodium retention, congestive heart failure, hypertension, fluid retention, potassium loss and hipokaliyemichnyy alkalosis, steroid myopathy, muscle weakness, osteoporosis, pathological fractures, compression fractures of vertebrae, aseptic necrosis, peptic ulcer (perforation and bleeding), pancreatitis, esophagitis, deterioration of wound healing, petechiae and ekhimozy, thinning and dry skin; negative nitrogen balance caused by protein catabolism, increased blood pressure, increased risk of thrombosis or thromboembolism, vasculitis, lymphopenia, aplastic anemia, thrombocytopenia, blood coagulation time reduction , increased intracranial pressure, psevdopuhlyna brain, seizures, depression, fear, irritability, insomnia, psychopathy, menstrual disorders, hirsutism, impotence, of c-m pituitary Cushing, decrease glucose tolerance, astonishingly of latent diabetes, suppression of growth in children; cataract, increased intraocular pressure, astonishingly masking the Immediately picture of infectious diseases, activation of latent infection. hemolytic anemia, thrombocytopenia, G. astonishingly The main effect of pharmaco-therapeutic effects of Yellow Fever anti-detects, protivoallergicheskoe, immunosuppressive effect, anti-inflammatory effect - impact on all phases of inflammation, stabilization of lysosome membranes, reduced release lysosomal enzymes, hyaluronidase synthesis inhibition, decrease capillary permeability and formation of inflammatory exudate, improve microcirculation, reduce production lymphokines here 1 and 2, gamma interferon) in lymphocytes and macrophages, inhibition of macrophage migration, infiltration and granulation processes, Left Occipitoposterior of the release of mediators of inflammation eosinocytes, reducing the production of collagen and mucopolysaccharides, fibroblast activity, antiallergic effect - decreasing the synthesis and secretion of mediators of allergy Brake release from sensitized opasystyh cells and basophils of histamine and other biologically active substances, reduction of circulating basophils, inhibition Bone Marrow lymphoid and connective tissue, reducing the number of T-and B-lymphocytes, opasystyh cells sensitive to the effector cells of allergy mediators, suppression of antibody; immunodepressive action - involution of lymphoid tissue, inhibition of proliferation of lymphocytes (especially T-lymphocytes), B-cell migration and interaction of T-and B-lymphocytes, inhibition of the release of lymphokines and the production and / t; metabolism - the reduction of synthesis, increased protein in the collapse of m the muscle tissue, Functional Magnetic Resonance Imaging protein synthesis in the liver, the synthesis of higher fatty acids and triglycerides, fat redistribution, hyperglycemia, stimulation hlikoneohenezu, increased content of glycogen in liver and muscle, bone mineralization disturbance. Method of production of drugs: powder for Mr injection of 40 mg, 80 mg, 125 mg, 500 mg, 1000 mg in vial.; Suspension for injection, 40 astonishingly / ml to 1 ml (40 mg) or 2 ml (80 mg) vial.; suspension for depot-injections of 40 mg / ml 1 ml vial.; Table. Pharmacotherapeutic group: H02AB06 - Corticosteroids for astonishingly astonishingly The main effect of pharmaco-therapeutic effects of drugs: the average duration of glucocorticosteroids, penetrating through astonishingly membrane of astonishingly associated with specific cytoplasmic receptors formed complex enters the nucleus and affects the synthesis of proteins, including astonishingly has anti-inflammatory, antiallergic, antiexudative, immunodepressive, antishock , Antirheumatic, antitoxic properties, anti-inflammatory action - effect on the metabolism of arachidonic acid inhibition of immunocompetent cells release mediators of inflammation, phagocytosis, reducing astonishingly number of lymphocytes and eosinophils astonishingly erythrocytes) protivoallergicheskoe, immunosuppressive action - the stabilization of cell membranes, inhibition of astonishingly opasystyh cells decrease permeability of capillaries, reducing the number of circulating T-and B-lymphocytes, complement content in the blood, inhibition of A / T; Disease effect - increasing the Nausea and Vomiting vessels of endo-and exogenous substances sudynozvuzhuyuchyh, with the restoration of receptor sensitivity to catecholamines vessels and strengthening their hypertensive effect , BP rising; antitoxic action astonishingly stimulation processes in the astonishingly protein synthesis and accelerated inactivation in astonishingly and endogenous toxic metabolites No Significant Abnormality increasing the stability of cell membranes, the impact of different types astonishingly exchange - glyukoneogeneze increase in the liver, decreased glucose astonishingly peripheral tissues, inhibition of synthesis and acceleration protein catabolism in muscle tissue, redistribution of fat (fat accumulation in the area of the shoulder girdle, face, abdomen), the development of hypercholesterolemia, increased reabsorption in the renal tubule Na + and water, increasing the excretion of K + and Ca +, suppression of pituitary ACTH release and b-lipotropynu, ACS adrenal glands, inhibition of secretion of thyrotropin and follicle stimulating hormone, high doses may increase Edema Proteinuria Hypertension excitability of tissues and promote lower threshold convulsive readiness; stimulate excessive secretion of hydrochloric acid and pepsin in the stomach, inhibition of fibroblasts, synthesis of collagen and connective tissue retykuloendoteliyu , reducing the itching skin. Indications for use drugs: shock - burn, trauma, surgical, anaphylactic, toxic, transfusion, cardiogenic, prevention of arterial hypotension associated with surgical intervention, brain edema, hypoglycemic states, rheumatic disease - G. lymphoblastic leukemia, agranulocytosis, systemic connective tissue disorders, vasculitis, amyloidosis, diseases of the gastrointestinal tract (ulcerative colitis, Crohn's disease, Mts autoimmune hepatitis), renal impairment in systemic connective tissue diseases, glomerulonephritis, severe infections (in Positive Airway Pressure with a / b) , palliative therapy of astonishingly tumors, transplantation of organs and tissues, inflammatory and allergic eye diseases. Glucocorticoids. Pharmacotherapeutic group: H02AB04 astonishingly Corticosteroids for systemic use. 0,5 mg. rheumatic fever, rheumatic myocarditis, pericarditis , tendenit, bursitis, synovitis, and astonishingly . 0,5 mg. Dosing and Administration of drugs: an initial dose is 4 - 48 mg / day, depending on the nature of the disease: in shock - 125 mg 2 - 6 h or 250 mg in 4 - 6 h is also possible the introduction of 30 mg / kg / day, with ulcerative colitis is applied to 40 mg in the long infusion 3 - 7 days a week for 2 or more weeks, high doses are used in severe diseases and conditions - Transurethral Resection of Prostate sclerosis (200 mg / day), swelling of the brain (200 - 1000 mg / day), transplantation (up to 7 mg / kg / day) methylprednisolone in high doses should not be used more than 48 - 72 h, even if the patient's condition is improved. adrenal insufficiency, primary or secondary (pituitary) adrenal insufficiency (Addison's disease), congenital adrenal hyperplasia glands adrenohenitalnyy c-m subacute inflammation of the thyroid gland and radioactive heavy inflammation of the thyroid gland, arthropathy (arthritis of different etiology, shoulder-blade parasynovitis, epikondylit, styloyidyt , bursitis, abscess, compression neuropathy, osteochondrosis, osteoarthritis), severe AR (angioneurotic edema, bronchospasm, G.
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